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Seminar Details

Date 25-5-2009
Time 10:30
Room/Location DISI-Sala Conferenze 3 piano
Title Evolutionary Algorithms for Protein Ligand Docking
Speaker Prof. Susmita Ghosh
Affiliation Jadavpur University, Kolkata, India
Link https://www.disi.unige.it/index.php?eventsandseminars/seminars
Abstract Protein-ligan docking is an important problem in bioinformatics and require a lot of search space exploration. The present work attempts to employ hybrid genetic algorithms (GAs) to solve the flexible-ligand docking problem i.e. predicting the binding conformation of a flexible ligand molecule into a rigid protein. Genetic algorithms are reputed to perform good optimization and search. We used a genetic algorithm to serach the space efficiently for this problem. Preliminary results obtained on a set of three protein-ligand complexes are encouraging.
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